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Genes with a G[AC]TAAGC and [GA]TGAGTCA motifs were enriched for amino acid biosynthesis

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At the neural level, LPS activates paraventricular nucleus microglia, reducing GABAergic inhibition of PVN-RVLM neurons (as indicated by decreased sIPSC frequency) and disinhibiting GABAA receptor-mediated suppression, thereby enhancing sympathetic hyperactivity (Han et al., 2021)